TRIM68 Antibodies

AND TRIM68 ELISA kits, TRIM68 Proteins

Many biological assays use antibodies to detect TRIM68, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM68 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM68 antibodies...

We validate the specificity of these antibodies to TRIM68 by testing them on tissues known to express TRIM68 positively and negatively. Browse below to find the TRIM68 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM68 Infographic by Boster Bio

All TRIM68 Products

Product

Figures

Specificity

Applications

Price

Anti-SS-56 TRIM68 Antibody

7 Q&As

Human

IHC, WB

$399
Cat # A11532
100μl

Anti-TRIM68 Antibody

Human, Mouse, Rat

$405
Cat # A11532-1
100ul

TRIM68 (NM_018073) Human Recombinant Protein

$1249
Cat # PROTQ6AZZ1
20 µg

TRIM68 (NM_018073) Human Over-expression Lysate

Human

$628
Cat # LS055128
100 µg

TRIM68 Overview

Facts about E3 ubiquitin-protein ligase TRIM68.

TRIM68 3D structure. Source: alphafold

E3 ubiquitin-protein ligase TRIM68 (TRIM68)

Functions as a ubiquitin E3 ligase.
Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.

Gene Information

Human
Gene Name:	TRIM68
Uniprot:	Q6AZZ1
Entrez:	55128

Family

Belongs to:

TRIM/RBCC family

Alternative Names

EC 6.3.2.-; FLJ10369; GC109MGC126176; RING finger protein 137RNF137; Ro/SSA1 related protein; SS56E3 ubiquitin-protein ligase TRIM68; SS-56SSA protein SS-56; tripartite motif containing 68; tripartite motif-containing 68; Tripartite motif-containing protein 68

Molecular Weight

Mass (kDA):
56.259 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (4598672..4608231, complement)

Tissue Specificity

Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.

Subcellular Localizations

Cytoplasm, perinuclear region. Nucleus. Colocalized with AR in nucleus.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Autoimmune Diseases
Autoimmune Reaction
Sjogren's Syndrome
Neoplasms
Lupus Erythematosus, Systemic
Autoimmunity
Cell Invasion
Cell Transformation, Neoplastic
Leukoencephalopathy, Progressive Multifocal

Melanoma
Carcinoma
Carcinogenesis
Prostatic Neoplasms
Hiv Infections
Leukemia

Pathways

Cell Growth
Methylation
Pathogenesis
Localization
Secretion
Demethylation

PTMs

Demethylation
Phosphorylation

Acetylation
Methylation

Ubiquitination

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM68

References

PMID: 11560955 by Billaut-Mulot O., et al. SS-56, a novel cellular target of autoantibody responses in Sjogren syndrome and systemic lupus erythematosus.

PMID: 11597395 by Chang G.T., et al. A novel gene on human chromosome 2p24 is differentially expressed between androgen-dependent and androgen-independent prostate cancer cells.