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Tab3 Antibodies
AND Tab3 ELISA kits, Tab3 Proteins
Many biological assays use antibodies to detect Tab3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tab3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tab3 antibodies...
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Tab3 Infographic by Boster Bio
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Tab3 Overview
Facts about TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Tab3)
Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2.
Mediator of MAP3K7 activation, respectively in the IL-1 and TNF signaling pathways.Plays a role in activation of NF-kappa-B and AP1 transcription factor (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Tab3 |
| Uniprot: | Q571K4 |
| Entrez: | 66724 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CG5330; ; dNap; dNap1; dNAP-1; MAP3K7IP3; MGC45404; mitogen-activated protein kinase kinase kinase 7 interacting protein 3; Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; NAP1; Nap-1; NF-kappa-B-activating protein 1; NFkB activating protein 1; p56/dCAF-4; TAB-3; TAK1-binding protein 3; TGF-beta activated kinase 1/MAP3K7 binding protein 3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; TGF-beta-activated kinase 1-binding protein 3
Molecular Weight
Mass (kDA):
79.029 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | X|X C1 |
| Sequence: | X; |
Diseases
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Infective Disorder
- Hiv Infections
- Sclerosis
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Bone Neoplasms
- Carcinoma
- Immunologic Deficiency Syndromes
- Patient Dependence On
Pathways
- Autophagy
- Localization
- Mating
- Osteoclast Differentiation
- Cell Cycle Checkpoint
- Response To Stress
- Induction Of Apoptosis
- Conjugation
- Cell Cycle Arrest
- Methylation
- Cell Cycle
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tab3
bosterbio.com/bosterbio-gene-info-cards/Tab3
References
PMID: 19927120 by Sato Y., et al. Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3.