TYRP1 Antibodies

AND TYRP1 ELISA kits, TYRP1 Proteins

Many biological assays use antibodies to detect TYRP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TYRP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TYRP1 antibodies...

We validate the specificity of these antibodies to TYRP1 by testing them on tissues known to express TYRP1 positively and negatively. Browse below to find the TYRP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TYRP1 Infographic by Boster Bio

All TYRP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Monoclonal Antibody

Human, Mouse

Flow Cytometry, IF, IHC

$486
Cat # M01959
100ug/vial

Anti-TRP1 Monoclonal Antibody

5 Q&As

Human

IP, IHC, WB

$370
Cat # M01959-1
100 μl

Anti-TRP1 TYRP1 Antibody

Human

IP, IHC, ICC, WB

$405
Cat # A01959
100ul

Human TYRP1 Recombinant Protein

SDS-PAGE

$350
Cat # PROTP17643
Starting from 10ug

TRP1 (TYRP1) (NM_000550) Human Over-expression Lysate

Human

$628
Cat # LS007306
100 µg

TYRP1 Overview

Facts about 5,6-dihydroxyindole-2-carboxylic acid oxidase.

TYRP1 3D structure. Source: alphafold

5,6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1)

Catalyzes the oxidation of 5,6-dihydroxyindole-2- carboxylic acid (DHICA) to indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions (PubMed:28661582). May regulate or influence the type of melanin synthesized (PubMed:22556244, PubMed:16704458).

Also to a lower extent, capable of hydroxylating tyrosine and producing saliva (By similarity). .

Gene Information

Human
Gene Name:	TYRP1
Uniprot:	P17643
Entrez:	7306

Family

Belongs to:

tyrosinase family

Alternative Names

b-PROTEIN; CAS25,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; CATB; EC 1.14.18; EC 1.14.18.-; EC 1.14.18.1; Glycoprotein 75; GP75DHICA oxidase; Melanoma antigen gp75; TRP-1; TRPTYRP; tyrosinase-related protein 1TRP1; TYRRP

Molecular Weight

Mass (kDA):
60.724 kDA

Genomic Context


Human

Location:	9p23
Sequence:	9; NC_000009.12 (12693375..12710285)

Tissue Specificity

Pigment cells.

Subcellular Localizations

Melanosome membrane; Single-pass type I membrane protein. Melanosome. Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.