Tetraspanin-33 Antibodies

AND Tspan33 ELISA kits, Tetraspanin-33 Proteins

Many biological assays use antibodies to detect Tetraspanin-33, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tetraspanin-33 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tetraspanin-33 antibodies...

We validate the specificity of these antibodies to Tetraspanin-33 by testing them on tissues known to express Tspan33 positively and negatively. Browse below to find the Tspan33 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tspan33 Infographic by Boster Bio

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Anti-Tetraspanin-33 TSPAN33 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A13091
100ul

Tspan33 Overview

Facts about Tetraspanin-33.

Tetraspanin-33 (Tspan33)

Plays an essential role in normal erythropoiesis (PubMed:17158226). It has a role in the differentiation of erythroid progenitors (PubMed:17158226).

Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:23035126). Negatively regulates ligand-induced Notch activity likely by regulating ADAM10 activity (By similarity).

Gene Information

Mouse
Gene Name:	Tspan33
Uniprot:	Q8R3S2
Entrez:	232670

Family

Belongs to:

tetraspanin (TM4SF) family

Alternative Names

hPen; PEN; Penumbra; proerythroblast new membrane; tetraspanin 33; tetraspanin-33; TSPAN33; tspan-33

Molecular Weight

Mass (kDA):
31.55 kDA

Genomic Context


Mouse

Location:	6\|6 A3.3
Sequence:	6;

Tissue Specificity

Predominantly expressed in erythroblasts.

Diseases

Malignant Neoplasms
Leukemia, Myelocytic, Acute
Brain Injuries
Dysmyelopoietic Syndromes
Ischemia
Leukemia
Inflammation
Brain Ischemia
Hepatitis, Chronic
Hepatitis B
Myeloid Leukemia
Cerebrovascular Accident

Brain Injuries, Acute
Cerebral Ischemia
Ischemic Stroke
Anemia
Traumatic Brain Injury
Hepatitis
Tissue Adhesions

Pathways

Response To Selenium Ion
Transport
Cell Adhesion
Regeneration
Regulation Of Calcium Ion-dependent Exocytosis
Transmembrane Transport
Cell Migration
Immune Response
Cell Growth

Exocytosis
Oogenesis
Calcium Ion-dependent Exocytosis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tspan33

References

PMID: 17158226 by Heikens M.J., et al. Penumbra encodes a novel tetraspanin that is highly expressed in erythroid progenitors and promotes effective erythropoiesis.

PMID: 23035126 by Haining E.J., et al. The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression.