ZC3HC1 Antibodies

AND ZC3HC1 ELISA kits, ZC3HC1 Proteins

Many biological assays use antibodies to detect ZC3HC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZC3HC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZC3HC1 antibodies...

We validate the specificity of these antibodies to ZC3HC1 by testing them on tissues known to express ZC3HC1 positively and negatively. Browse below to find the ZC3HC1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZC3HC1 Infographic by Boster Bio

All ZC3HC1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NIPA ZC3HC1 Antibody

7 Q&As

Human, Monkey, Mouse, Rat

$399
Cat # A07135
100μl

NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2322
1 kit, containing two 96-well plates and all necessary reagents

Anti-NIPA (S350) ZC3HC1 Antibody

Human, Mouse

IF, WB

$405
Cat # A07135S350
100ul

Anti-NIPA (phospho-S354) ZC3HC1 Antibody

Human, Mouse, Rat

$482
Cat # A07135S354
100ul

NIPA (ZC3HC1) (NM_016478) Human Over-expression Lysate

Human

$628
Cat # LS051530
100 µg

ZC3HC1 Overview

Facts about Nuclear-interacting partner of ALK.

ZC3HC1 3D structure. Source: alphafold

Nuclear-interacting partner of ALK (ZC3HC1)

Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complicated, restricting CCNB1 ubiquitination action to interphase.

Its inactivation leads to nuclear accumulation of CCNB1 in interphase and premature mitotic entry. Might have an antiapoptotic role in NPM-ALK-mediated signaling events.

Gene Information

Human
Gene Name:	ZC3HC1
Uniprot:	Q86WB0
Entrez:	51530

Family

Belongs to:

No superfamily

Alternative Names

C3HC type 1; FBXO50; zinc finger, C3HC-type containing 1

Molecular Weight

Mass (kDA):
55.262 kDA

Genomic Context


Human

Location:	7q32.2
Sequence:	7; NC_000007.14 (130018286..130051451, complement)

Tissue Specificity

Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes.