TSFM Antibodies

AND TSFM ELISA kits, TSFM Proteins

Many biological assays use antibodies to detect TSFM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TSFM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TSFM antibodies...

We validate the specificity of these antibodies to TSFM by testing them on tissues known to express TSFM positively and negatively. Browse below to find the TSFM antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TSFM Infographic by Boster Bio

All TSFM Products

Product

Figures

Specificity

Applications

Price

Anti-TSFM Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A08656
100ul

Human TSFM Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP43897
Starting from 20ug

Anti-TSFM Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M08656
100 μl/vial

Anti-EF-Ts/TSFM Antibody Picoband™

Human

ELISA, WB

$370
Cat # A08656-2
100 μg/vial

TSFM Overview

Facts about Elongation factor Ts, mitochondrial.

TSFM 3D structure. Source: alphafold

Elongation factor Ts, mitochondrial (TSFM)

Associates with the EF-Tu.
GDP complex and induces the exchange of GDP to GTP.

It remains bound to the aminoacyl-tRNA. EF- Tu.

Gene Information

Human
Gene Name:	TSFM
Uniprot:	P43897
Entrez:	10102

Family

Belongs to:

EF-Ts family

Alternative Names

COXPD3; EFTS; EF-Ts; EFTSMT; EF-Tsmt; mitochondrial elongation factor Ts; mitochondrial; Ts translation elongation factor, mitochondrial

Molecular Weight

Mass (kDA):
35.391 kDA

Genomic Context


Human

Location:	12q14.1
Sequence:	12; NC_000012.12 (57782745..57802856)

Tissue Specificity

Expressed in all tissues, with the highest levels of expression in skeletal muscle, liver and kidney.

Subcellular Localizations

Mitochondrion.

Diseases

Sclerosis
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Hypertrophic Cardiomyopathy
Multiple Sclerosis
Cardiomyopathies
Hypertrophy
Mitochondrial Dna Depletion
Mitochondrial Diseases
Retroperitoneal Neoplasms
Malignant Neoplasm Of Lung
Fetal Growth Retardation
Malignant Neoplasms
Neoplasms

Liver Dysfunction
Celiac Disease
Rheumatoid Arthritis
Dysequilibrium Syndrome
Extra Unidentified Structurally Abnormal Chromosome (disorder)
Cell Transformation, Neoplastic
Acidosis

Interacting Proteins

CEP70
RALBP1

Pathways

Translation
Mitochondrial Translation
Methylation
Cell Cycle
Oxidative Phosphorylation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TSFM

References

PMID: 7615523 by Xin H., et al. Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver.

PMID: 17033963 by Smeitink J.A.M., et al. Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs.