TRPM4 Antibodies

AND TRPM4 ELISA kits, TRPM4 Proteins

Many biological assays use antibodies to detect TRPM4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRPM4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRPM4 antibodies...

We validate the specificity of these antibodies to TRPM4 by testing them on tissues known to express TRPM4 positively and negatively. Browse below to find the TRPM4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRPM4 Infographic by Boster Bio

All TRPM4 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRPM4 Antibody Picoband®

6 Q&As

Human

IHC, WB

$370
Cat # PB9902
100 μg/vial

Anti-TRPM4 Mouse Monoclonal Antibody [Clone ID: OTI10H5]

Dog, Human, Monkey

IHC, WB

$523
Cat # M02130
100 µl

TRPM4 (NM_017636) Human Over-expression Lysate

Human

$960
Cat # LS054795
100 µg

TRPM4 Overview

Facts about Transient receptor potential cation channel subfamily M member 4.

TRPM4 3D structure. Source: alphafold

Transient receptor potential cation channel subfamily M member 4 (TRPM4)

Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization (PubMed:12015988, PubMed:29211723). While it's activated by increase in intracellular Ca(2+), it's impermeable to it (PubMed:12015988).

Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It consequently plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc.

Gene Information

Human
Gene Name:	TRPM4
Uniprot:	Q8TD43
Entrez:	54795

Family

Belongs to:

transient receptor (TC 1.A.4) family

Alternative Names

Calcium-activated non-selective cation channel 1; FLJ20041; hTRPM4; Long transient receptor potential channel 4; LTRPC4; LTrpC-4; melastatin-4; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; TRPM4B

Molecular Weight

Mass (kDA):
134.301 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49157792..49211841)

Tissue Specificity

Widely expressed with a high expression in intestine and prostate. In brain, it is both expressed in whole cerebral arteries and isolated vascular smooth muscle cells. Prominently expressed in Purkinje fibers. Expressed at higher levels in T-helper 2 (Th2) cells as compared to T-helper 1 (Th1) cells.

Subcellular Localizations

[Isoform 1]: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus.; [Isoform 2]: Cell membrane. Endoplasmic reticulum. Golgi apparatus.