MBTD1 Antibodies

AND MBTD1 ELISA kits, MBTD1 Proteins

Many biological assays use antibodies to detect MBTD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MBTD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MBTD1 antibodies...

We validate the specificity of these antibodies to MBTD1 by testing them on tissues known to express MBTD1 positively and negatively. Browse below to find the MBTD1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MBTD1 Infographic by Boster Bio

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MBTD1 (NM_017643) Human Recombinant Protein

$1249
Cat # PROTQ05BQ5
20 µg

MBTD1 Overview

Facts about MBT domain-containing protein 1.

MBTD1 3D structure. Source: alphafold

MBT domain-containing protein 1 (MBTD1)

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, likely via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).

Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4. .

Gene Information

Human
Gene Name:	MBTD1
Uniprot:	Q05BQ5
Entrez:	54799

Family

Belongs to:

No superfamily

Alternative Names

MBT domain-containing protein 1

Molecular Weight

Mass (kDA):
70.547 kDA

Genomic Context


Human

Location:	17q21.33
Sequence:	17; NC_000017.11 (51177419..51260511, complement)

Subcellular Localizations

Nucleus.

Interacting Proteins

EPC1
HIST1H4A

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MBTD1

References

PMID: 19841675 by Eryilmaz J., et al. Structural studies of a four-MBT repeat protein MBTD1.

PMID: 23915195 by De Braekeleer E., et al. Recurrent translocation (10;17)(p15;q21) in acute poorly differentiated myeloid leukemia likely results in ZMYND11-MBTD1 fusion.