TRMT10A Antibodies

AND TRMT10A ELISA kits, TRMT10A Proteins

Many biological assays use antibodies to detect TRMT10A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRMT10A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRMT10A antibodies...

We validate the specificity of these antibodies to TRMT10A by testing them on tissues known to express TRMT10A positively and negatively. Browse below to find the TRMT10A antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRMT10A Infographic by Boster Bio

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TRMT10A Overview

Facts about tRNA methyltransferase 10 homolog A.

TRMT10A 3D structure. Source: alphafold

tRNA methyltransferase 10 homolog A (TRMT10A)

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Gene Information

Human
Gene Name:	TRMT10A
Uniprot:	Q8TBZ6
Entrez:	93587

Family

Belongs to:

class IV-like SAM-binding methyltransferase superfamily

Alternative Names

MGC27034; RNA (guanine-9-) methyltransferase domain containing 2

Molecular Weight

Mass (kDA):
39.719 kDA

Genomic Context


Human

Location:	4q23
Sequence:	4; NC_000004.12 (99546711..99564039, complement)

Tissue Specificity

Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencephalon, at later stages.

Subcellular Localizations

Nucleus. Nucleus, nucleolus.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRMT10A

References

PMID: 23042678 by Vilardo E., et al. A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis.

PMID: 24204302 by Igoillo-Esteve M., et al. tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans.