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- Table of Contents
Facts about Voltage-dependent calcium channel subunit alpha-2/delta-4.
Human | |
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Gene Name: | CACNA2D4 |
Uniprot: | Q7Z3S7 |
Entrez: | 93589 |
Belongs to: |
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calcium channel subunit alpha-2/delta family |
calcium channel, voltage-dependent, alpha 2/delta subunit 4; RCD4; voltage-dependent calcium channel subunit alpha-2/delta-4; voltage-gated calcium channel alpha(2)delta-4 subunit; Voltage-gated calcium channel subunit alpha-2/delta-4
Mass (kDA):
127.938 kDA
Human | |
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Location: | 12p13.33 |
Sequence: | 12; NC_000012.12 (1791963..1922606, complement) |
Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level).
Membrane; Single-pass type I membrane protein.
PMID: 12181424 by Qin N., et al. Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
PMID: 17033974 by Wycisk K.A., et al. Mutation in the auxiliary calcium-channel subunit CACNA2D4 causes autosomal recessive cone dystrophy.