TRIM8 Antibodies

AND TRIM8 ELISA kits, TRIM8 Proteins

Many biological assays use antibodies to detect TRIM8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM8 antibodies...

We validate the specificity of these antibodies to TRIM8 by testing them on tissues known to express TRIM8 positively and negatively. Browse below to find the TRIM8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM8 Infographic by Boster Bio

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GERP (TRIM8) (NM_030912) Human Recombinant Protein

$1249
Cat # PROTQ9BZR9
20 µg

TRIM8 Overview

Facts about E3 ubiquitin-protein ligase TRIM8.

TRIM8 3D structure. Source: alphafold

E3 ubiquitin-protein ligase TRIM8 (TRIM8)

E3 ubiquitin-protein ligase that plays different roles in immune pathways. Participates in the activation of interferon- gamma signaling by encouraging proteasomal degradation of the repressor SOCS1 (PubMed:12163497).

Plays a positive part in the TNFalpha and IL-1beta signaling pathways. Mechanistically, induces the'lys-63' polyubiquitination of MAP3K7/TAK1 part resulting in the activation of NF-kappa-B (PubMed:22084099, PubMed:23152791).

Gene Information

Human
Gene Name:	TRIM8
Uniprot:	Q9BZR9
Entrez:	81603

Family

Belongs to:

TRIM/RBCC family

Alternative Names

EC 6.3.2.-; GERP; GERPRING finger protein 27glioblastoma expressed ring finger protein; Glioblastoma-expressed RING finger protein; RNF27probable E3 ubiquitin-protein ligase TRIM8; tripartite motif containing 8; tripartite motif protein TRIM8; tripartite motif-containing 8; Tripartite motif-containing protein 8