TRIM39 Antibodies

AND TRIM39 ELISA kits, TRIM39 Proteins

Many biological assays use antibodies to detect TRIM39, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM39 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM39 antibodies...

We validate the specificity of these antibodies to TRIM39 by testing them on tissues known to express TRIM39 positively and negatively. Browse below to find the TRIM39 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM39 Infographic by Boster Bio

All TRIM39 Products

Product

Figures

Specificity

Applications

Price

RNF23 (TRIM39) (NM_172016) Human Recombinant Protein

$1249
Cat # PROTQ9HCM9
20 µg

Anti-RNF23 (TRIM39) Mouse Monoclonal Antibody [Clone ID: OTI2A6]

Human, Mouse, Rat

$523
Cat # M09149
100 µl

RNF23 (TRIM39) (NM_172016) Human Over-expression Lysate

Human

$628
Cat # LS056658
100 µg

TRIM39 Overview

Facts about E3 ubiquitin-protein ligase TRIM39.

TRIM39 3D structure. Source: alphafold

E3 ubiquitin-protein ligase TRIM39 (TRIM39)

E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and following proteasome-mediated degradation of the pro-apoptotic protein MOAP1.

Gene Information

Human
Gene Name:	TRIM39
Uniprot:	Q9HCM9
Entrez:	56658

Family

Belongs to:

TRIM/RBCC family

Alternative Names

MGC32984; RING finger protein 23RNF23TFPtripartite motif-containing 39; Testis-abundant finger protein; TRIM39B; tripartite motif containing 39; tripartite motif-containing protein 39

Molecular Weight

Mass (kDA):
59.69 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (30326469..30343729)

Tissue Specificity

Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.

Subcellular Localizations

[Isoform 1]: Cytoplasm, cytosol. Mitochondrion. Nucleus. Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when colocalized with MOAP1. Colocalizes with CDKN1A in the nucleus.; [Isoform 2]: Nucleus. Colocalizes with CDKN1A in the nucleus.

Diseases

Carcinoma
Liver Carcinoma
Behcet Syndrome
Social Disinhibition
Chromosome Inversion
Acute Monocytic Leukemia
Autoimmune Diseases
Growth Retardation
Autoimmune Reaction

Neoplasms
Leukemia
Monocytic Leukemia
Genotoxic Stress

Interacting Proteins

CCNC
DCUN1D1
EIF4A2
LNX1
LXN

MED18
NCK1
POLI
PRPF3
PSMA6

PSMD9
SMCO3
TRIM17
TRIM21
TTC32

UBAC1
UBE2D1
UBE2D3
UBE2D4
UBE2E2

UBE2E3
UBE2K
UBTD1
UBXN1
UBXN6

ZKSCAN4
ZNF26

Pathways

Release Of Cytochrome C From Mitochondria
Cell Death
Cell Cycle
Cellular Homeostasis
Cell Growth

PTMs

Phosphorylation

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM39

References

PMID: 11006080 by Orimo A., et al. Molecular cloning of testis-abundant finger protein/ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC.

PMID: 16702430 by Shiina T., et al. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.