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- Table of Contents
Facts about TLR4 interactor with leucine rich repeats.
Part of the TLR4 signaling complex.
Mediate the innate immune response to bacterial lipopolysaccharide (LPS) resulting in cytokine secretion..
Human | |
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Gene Name: | TRIL |
Uniprot: | Q7L0X0 |
Entrez: | 9865 |
Belongs to: |
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No superfamily |
; KIAA0644; TLR4 Interactor With Leucine Rich Repeats; TRIL
Mass (kDA):
88.723 kDA
Human | |
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Location: | 7p14.3 |
Sequence: | 7; NC_000007.14 (28953358..28958330, complement) |
Highly expressed in the brain, ovary, small intestine and spleen.
Membrane; Single-pass type I membrane protein.
PMID: 19710467 by Carpenter S., et al. TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain.
PMID: 26477546 by Srour M., et al. Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.