TRERF1 Antibodies

AND TRERF1 ELISA kits, TRERF1 Proteins

Many biological assays use antibodies to detect TRERF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRERF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRERF1 antibodies...

We validate the specificity of these antibodies to TRERF1 by testing them on tissues known to express TRERF1 positively and negatively. Browse below to find the TRERF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRERF1 Infographic by Boster Bio

All TRERF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TREF1 TRERF1 Antibody

1 Q&As

Human, Mouse

ELISA, IHC-P, IF (paraffin)

$335
Cat # A30550
100ul

TReP132 (TRERF1) (NM_033502) Human Over-expression Lysate

Human

$960
Cat # LS055809
100 µg

TRERF1 Overview

Facts about Transcriptional-regulating factor 1.

TRERF1 3D structure. Source: alphafold

Transcriptional-regulating factor 1 (TRERF1)

Binds DNA and activates transcription of CYP11A1.
Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.

Gene Information

Human
Gene Name:	TRERF1
Uniprot:	Q96PN7
Entrez:	55809

Family

Belongs to:

No superfamily

Alternative Names

BCAR2; Breast cancer estrogen resistance 2RAPAHSA277276; dJ139D8.5; FLJ21198; rapa-1; rapa-2; RP1-139D8.5; transcriptional regulating factor 1; transcriptional regulating protein 132; transcriptional-regulating factor 1; Transcriptional-regulating protein 132; TREP132; TReP-132; Zinc finger protein rapa; Zinc finger transcription factor TReP-132

Molecular Weight

Mass (kDA):
132.256 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (42224931..42452224, complement)

Tissue Specificity

Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Mammary Neoplasms
Malignant Neoplasm Of Breast
Malignant Neoplasms
Tumor Progression
Carcinoma
Abnormal Degeneration
Cell Invasion
Neoplasm Metastasis
Congenital Abnormality
Adrenal Gland Neoplasms
Kidney Neoplasm

Protrusion
Congenital Lordosis Due To Bony Malformation
Lordosis
Swayback
Mental Disorders
Renal Cell Carcinoma

Pathways

Cell Proliferation
Cell Cycle
Cell Differentiation
Brain Development
Cell Growth
V(d)j Recombination

Localization

PTMs

Phosphorylation

Cleavage

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRERF1

References

PMID: 11349124 by Gizard F., et al. A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression.

PMID: 18351453 by van Agthoven T., et al. Functional identification of genes causing estrogen independence of human breast cancer cells.