TREML2 Antibodies

AND TREML2 ELISA kits, TREML2 Proteins

Many biological assays use antibodies to detect TREML2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TREML2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TREML2 antibodies...

We validate the specificity of these antibodies to TREML2 by testing them on tissues known to express TREML2 positively and negatively. Browse below to find the TREML2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TREML2 Infographic by Boster Bio

All TREML2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human TREML2 ELISA Kit PicoKine®

10 Q&As

Human

ELISA

$750
Cat # EK1985
96 wells/kit, with removable strips.

Anti-TRML2 TREML2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08894
100ul

TREML2 (NM_024807) Human Over-expression Lysate

Human

$628
Cat # LS079865
100 µg

Anti-TREML2 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08894-1
100 μg/vial

TREML2 Overview

Facts about Trem-like transcript 2 protein.

TREML2 3D structure. Source: alphafold

Trem-like transcript 2 protein (TREML2)

Cell surface receptor that may play a role in the innate and adaptive immune reaction. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enriches T-cell activation.

Gene Information

Human
Gene Name:	TREML2
Uniprot:	Q5T2D2
Entrez:	79865

Family

Belongs to:

No superfamily

Alternative Names

C6orf76; dJ238O23.1; FLJ13693; MGC149715; MGC149716; TLT2; TLT-2; TREML2; trem-like transcript 2 protein; triggering receptor expressed on myeloid cells-like 2; triggering receptor expressed on myeloid cells-like protein 2; UNQ6268/PRO20473

Molecular Weight

Mass (kDA):
35.127 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (41189749..41201233, complement)

Tissue Specificity

Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Inflammation
Sclerosis
Periodontitis
Osteopenia
Inflammatory Bowel Diseases
Multiple Sclerosis
Tissue Adhesions
Autoimmune Diseases
Intestinal Diseases
Contact Dermatitis
Arthritis
Malignant Neoplasms

Neoplasms
Innate Immune Response
Bacterial Infections
Rheumatoid Arthritis
Contact Hypersensitivity
Tissue Damage

Pathways

Immune Response
Osteoclast Differentiation
Cell Activation
Cytokine Production
Cell Development
T Cell Activation
Innate Immune Response
Bone Remodeling

Hypersensitivity
Bone Resorption

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TREML2

References

PMID: 12645956 by Allcock R.J.N., et al. The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44.

PMID: 18650384 by Hashiguchi M., et al. Triggering receptor expressed on myeloid cell-like transcript 2 (TLT- 2) is a counter-receptor for B7-H3 and enhances T cell responses.