TRAM2 Antibodies

Translocating chain-associated membrane protein 2 (TRAM2)

Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with all the activity of the translocon.

This coupling may raise the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be crucial for the function of molecular chaperones involved in collagen folding. Required for proper functioning of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for controlled choice translocation (RAT) (PubMed:27499293).

Gene Information

Human
Gene Name:	TRAM2
Uniprot:	Q15035
Entrez:	9697

Family

Belongs to:
TRAM family

Alternative Names

KIAA0057TRAM-like protein; translocating chain-associated membrane protein 2; translocation associated membrane protein 2

Molecular Weight

Mass (kDA):
43.328 kDA

Genomic Context

Human
Location:	6p12.2
Sequence:	6; NC_000006.12 (52497405..52577060, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

• Insulin Resistance
• Liver Diseases
• Malnutrition
• Polycystic Kidney Diseases
• Obesity
• Pregnancy Complications
• Autosomal Recessive Polycystic Kidney Disease
• Pain

• Inflammation
• Speech Disorders
• Somatosensory Disorders

Pathways

• Quorum Sensing
• Osteoclast Differentiation
• Translation
• Brain Development

PTMs

• Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAM2

Steve Boster Bio - Best Uses Of The TRAM2 Marker

This article will explain the background and current projects that Steven Boster is involved in. You will also find information about his educational history and future plans. You will then learn more about the TRAM2 marking. You will be amazed at the many uses this device has! It is easy to use and is easy to store. This is a great tool to add fun to your day.

History of Steven Boster

A detailed search of Steve Boster's history can reveal many personal details. Public records include email addresses, addresses of known relatives, telephone numbers and current and past phone numbers. You can refine the search by location, state, and age using public records. For example, you could use the state- and city filters to find Steve Boster’s birthplace. You can also narrow your search if you're trying to find his current job by selecting the right place.

Steve Boster's story began in Joliet (Illinois) as a young child. He was born June 6, 1959 to James Meier (and Evelyn Meier) He was a retail sales manager for many years, and he served in the U.S. Army. His parents were also members of Concordia Hall, Staunton. His surviving family includes Crystal Boster-Peck and Natosha Boster, 2 daughters, Natosha and Crystal, as well six grandchildren. He was also survived by four brothers, Jack Boster. Sandra Blanton and Jack Boster. Lisa Milton and Jonathan Boster.