TRAK2 Antibodies

AND TRAK2 ELISA kits, TRAK2 Proteins

Many biological assays use antibodies to detect TRAK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAK2 antibodies...

We validate the specificity of these antibodies to TRAK2 by testing them on tissues known to express TRAK2 positively and negatively. Browse below to find the TRAK2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAK2 Infographic by Boster Bio

All TRAK2 Products

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Anti-GRIF-1 TRAK2 Antibody

Human

ELISA, IHC

$380
Cat # A07746
100ul

TRAK2 Overview

Facts about Trafficking kinesin-binding protein 2.

TRAK2 3D structure. Source: alphafold

Trafficking kinesin-binding protein 2 (TRAK2)

May regulate endosome-to-lysosome trafficking of membrane cargo, such as EGFR. .

Gene Information

Human
Gene Name:	TRAK2
Uniprot:	O60296
Entrez:	66008

Family

Belongs to:

milton family

Alternative Names

ALS2CR3GRIF1; CALS-C; GRIF-1; KIAA0549amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; OIP98Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein; trafficking kinesin-binding protein 2; trafficking protein, kinesin binding 2

Molecular Weight

Mass (kDA):
101.419 kDA

Genomic Context


Human

Location:	2q33.1
Sequence:	2; NC_000002.12 (201377207..201451577, complement)

Tissue Specificity

Widely expressed, with highest expression in heart.

Subcellular Localizations

Cytoplasm. Early endosome. Mitochondrion. Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity).

Diseases

Carcinoma
Malignant Neoplasms
Optic Atrophy
Sclerosis
Neoplasm Metastasis
Primary Lateral Sclerosis
Metastatic Malignant Neoplasm To The Lymph Node
Neurodegenerative Disorders
Bone Neoplasms
Hypoxia
Carcinoma, Papillary
Amyotrophic Lateral Sclerosis
Neoplasm Invasiveness

Nervousness
Papillary Thyroid Carcinoma
Anoxia
Esophageal Neoplasms
Dysequilibrium Syndrome
Cell Invasion
Malignant Squamous Cell Neoplasm

Pathways

Transport
Mitochondrial Transport
Mitochondrial Fusion
Gene Silencing
Glycosylation
Microtubule-based Transport

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAK2

References

PMID: 11161814 by Hadano S., et al. Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2.

PMID: 16630562 by Fransson S., et al. The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.