E3 ubiquitin-protein ligase TRAF7 (TRAF7)

E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators.

Induces apoptosis when overexpressed. .