TP53INP1 Antibodies

AND TP53INP1 ELISA kits, TP53INP1 Proteins

Many biological assays use antibodies to detect TP53INP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TP53INP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TP53INP1 antibodies...

We validate the specificity of these antibodies to TP53INP1 by testing them on tissues known to express TP53INP1 positively and negatively. Browse below to find the TP53INP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TP53INP1 Infographic by Boster Bio

All TP53INP1 Products

Product

Figures

Specificity

Applications

Price

Anti-p53DINP1 TP53INP1 Antibody

2 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04229
100ul

Anti-p53 DINP1 Rabbit Monoclonal Antibody

7 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M04229-1
100 μl/vial

p53 DINP1 (TP53INP1) (NM_033285) Human Over-expression Lysate

Human

$628
Cat # LS094241
100 µg

TP53INP1 Overview

Facts about Tumor protein p53-inducible nuclear protein 1.

TP53INP1 3D structure. Source: alphafold

Tumor protein p53-inducible nuclear protein 1 (TP53INP1)

Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy.

In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.

Gene Information

Human
Gene Name:	TP53INP1
Uniprot:	Q96A56
Entrez:	94241

Family

Belongs to:

No superfamily

Alternative Names

DKFZp434M1317; FLJ22139; p53DINP1; P53DINP1p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; SIPStress-induced protein; Teap; TP53DINP1; TP53INP1A; TP53INP1B; tumor protein p53 inducible nuclear protein 1; tumor protein p53-inducible nuclear protein 1

Molecular Weight

Mass (kDA):
27.366 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (94925972..94949378, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Leukemia
Cell Transformation, Neoplastic
Prostatic Neoplasms
Pancreatitis
Acute Pancreatitis
Malignant Neoplasm Of Prostate
Malignant Neoplasm Of Breast
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Metastatic Malignant Neoplasm To The Lymph Node

Adenocarcinoma
Malignant Neoplasm Of Pancreas
Cell Invasion
Neuroblastoma
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Neoplasm Metastasis

Interacting Proteins

GABARAPL1
GABARAPL2
MAP1LC3C

Pathways

Cell Cycle
Cell Death
Cell Proliferation
Cell Growth
Cell Cycle Arrest
Autophagy
Methylation
Pathogenesis
Dna Methylation
Cell Migration
Programmed Cell Death
Cellular Senescence

Reverse Transcription
Induction Of Apoptosis
Senescence
Cell Adhesion
Response To Wounding
Nuclear Export
Replicative Senescence

PTMs

Phosphorylation

Methylation

Cleavage

Research Areas

Apoptosis
Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TP53INP1

References

PMID: 11511362 by Okamura S., et al. p53DINP1, a p53-inducible gene, regulate p53-dependent apoptosis.

PMID: 12067065 by Tomasini R., et al. p53-dependent expression of the stress-induced protein (SIP).

9 Publications of Boster TP53INP1 Antibodies & ELISA Kits

PubMed ID: 10.3892/or.2015.3725, Cycloartan-24-ene-1α,2α,3β-triol, a cycloartane-type triterpenoid from the re...
PubMed ID: 10.3892/etm.2019.8007, Downregulation of microRNA‑3934‑5p induces apoptosis and inhibits the prolif...
PubMed ID: 10.3389/fphys.2018.00941, Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and I...
PubMed ID: 10.1039/C5TB00514K, Design of magnetic nanoparticles for hepatocellular carcinoma treatment using th...
PubMed ID: 10.1016/j.jcma.2018.03.013, Involvement of S100A4/Mts1 and associated proteins in the protective effect of f...
PubMed ID: 10.1016/j.ejphar.2020.172982, Long non-coding RNA ROR confers arsenic trioxide resistance to HepG2 cells by in...
PubMed ID: 10.1016/j.ab.2018.08.004, Parallel study on protein O-GlcNAcylation in prostate cancer cell with a sensiti...
PubMed ID: 33603839, Liu L,Zhang J,Liu Y. MicroRNA-1323 serves as a biomarker in gestational diabetes...
PubMed ID: 25651840, Xiao S, Zhou Y, Yi W, Luo G, Jiang B, Tian Q, Li Y, Xue M. Int J Oncol. 2015 Apr...

*More publications can be found for each product on its corresponding product page