TNNI1 Antibodies

AND TNNI1 ELISA kits, TNNI1 Proteins

Many biological assays use antibodies to detect TNNI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNNI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNNI1 antibodies...

We validate the specificity of these antibodies to TNNI1 by testing them on tissues known to express TNNI1 positively and negatively. Browse below to find the TNNI1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: TNNI3

TNNI1 Infographic by Boster Bio

All TNNI1 Products

Product

Figures

Specificity

Applications

Price

Human TNNI1 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP19237
Starting from 20ug

Anti-TNNI1 Mouse Monoclonal Antibody [Clone ID: OTI8H8]

Human, Mouse, Rat

IHC, WB

$560
Cat # M07080
100 µl

Anti-TNNI1 Rabbit Monoclonal Antibody

Human

IP, IHC, WB

$370
Cat # M07080-1
100 μl/vial

Anti-TNNI1 Antibody Picoband™

Human

IHC, WB

$370
Cat # A07080-1
100 μg/vial

TNNI1 (NM_003281) Human Over-expression Lysate

Human

$628
Cat # LS007135
100 µg

TNNI1 Overview

Facts about Troponin I, slow skeletal muscle.

TNNI1 3D structure. Source: alphafold

Troponin I, slow skeletal muscle (TNNI1)

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. .

Gene Information

Human
Gene Name:	TNNI1
Uniprot:	P19237
Entrez:	7135

Family

Belongs to:

troponin I family

Alternative Names

DKFZp451O223; slow-twitch isoform; SSTNI; TNN1; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow; troponin I, slow skeletal muscle

Molecular Weight

Mass (kDA):
21.692 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (201403784..201421730, complement)

Tissue Specificity

Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.

Diseases

Hypertrophy
Hypertrophic Cardiomyopathy
Cardiomyopathies
Acute Coronary Syndrome
Cardiomyopathy, Hypertrophic, Familial

Interacting Proteins

MDFI
PNMA1
TNNC1

Pathways

Striated Muscle Contraction
Muscle Contraction
Response To Stress
Membrane Depolarization
Cell Development
Regulation Of Striated Muscle Contraction
Cell Communication

Interphase
Localization

PTMs

Acetylation

Phosphoprotein

Research Areas

Cell Biology
Cellular Markers
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNNI1

References

PMID: 2365354 by Wade R., et al. cDNA sequence, tissue-specific expression, and chromosomal mapping of the human slow-twitch skeletal muscle isoform of troponin I.

PMID: 8144655 by Corin S.J., et al. Structure and expression of the human slow twitch skeletal muscle troponin I gene.