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- Table of Contents
Facts about Transmembrane protease serine 4.
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Human | |
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Gene Name: | TMPRSS4 |
Uniprot: | Q9NRS4 |
Entrez: | 56649 |
Belongs to: |
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peptidase S1 family |
CAPH2; Channel-activating protease 2; EC 3.4.21; EC 3.4.21.4; EC 3.4.21.43; Membrane-type serine protease 2; MT-SP2type II membrane serine protease; TMPRSS3EC 3.4.21.-; transmembrane protease serine 4; transmembrane protease, serine 4; transmembrane serine protease 3
Mass (kDA):
48.246 kDA
Human | |
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Location: | 11q23.3 |
Sequence: | 11; NC_000011.10 (118077012..118125505) |
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
Membrane; Single-pass type II membrane protein.
PMID: 10825129 by Wallrapp C., et al. A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.