Transmembrane protein 231 Antibodies

AND TMEM231 ELISA kits, Transmembrane protein 231 Proteins

Many biological assays use antibodies to detect Transmembrane protein 231, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transmembrane protein 231 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transmembrane protein 231 antibodies...

We validate the specificity of these antibodies to Transmembrane protein 231 by testing them on tissues known to express TMEM231 positively and negatively. Browse below to find the TMEM231 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM231 Infographic by Boster Bio

All TMEM231 Products

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Specificity

Applications

Price

TMEM231 (NM_001077419) Human Recombinant Protein

$813
Cat # PROTQ9H6L2
20 µg

TMEM231 (NM_001077416) Human Over-expression Lysate

Human

$628
Cat # LS079583
100 µg

TMEM231 Overview

Facts about Transmembrane protein 231.

TMEM231 3D structure. Source: alphafold

Transmembrane protein 231 (TMEM231)

Transmembrane part of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier which prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).

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Gene Information

Human
Gene Name:	TMEM231
Uniprot:	Q9H6L2
Entrez:	79583

Family

Belongs to:

TMEM231 family

Alternative Names

ALYE870; FLJ22167; PRO1886; transmembrane protein 231

Molecular Weight

Mass (kDA):
36.059 kDA

Genomic Context


Human

Location:	16q23.1
Sequence:	16; NC_000016.10 (75536741..75556286, complement)

Subcellular Localizations

Cell projection, cilium membrane; Multi-pass membrane protein. Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone.

Diseases

Apraxias
Respiration Abnormal
Oculomotor Apraxia
Developmental Delay (disorder)
Familial Aplasia Of The Vermis
Polydactyly

Retinal Diseases

Interacting Proteins

KRT31
KRT40
NOTCH2NL

Pathways

Transport
Intraflagellar Transport

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM231

References

PMID: 26595381 by Lambacher N.J., et al. TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.

PMID: 23012439 by Srour M., et al. Mutations in TMEM231 cause Joubert syndrome in French Canadians.