THAP5 Antibodies

AND THAP5 ELISA kits, THAP5 Proteins

Many biological assays use antibodies to detect THAP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with THAP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop THAP5 antibodies...

We validate the specificity of these antibodies to THAP5 by testing them on tissues known to express THAP5 positively and negatively. Browse below to find the THAP5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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THAP5 Infographic by Boster Bio

All THAP5 Products

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Product

Figures

Specificity

Applications

Price

Anti-THAP5 Mouse Monoclonal Antibody [Clone ID: OTI2D7]

Human

$523
Cat # M12430
100 µl

THAP5 (NM_182529) Human Over-expression Lysate

Human

$628
Cat # LS168451
100 µg

THAP5 Overview

Facts about THAP domain-containing protein 5.

THAP5 3D structure. Source: alphafold

THAP domain-containing protein 5 (THAP5)

Has sequence-specific DNA-binding activity and may serve as transcriptional repressor (in vitro) (PubMed:21110952). Might be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).

Gene Information

Human
Gene Name:	THAP5
Uniprot:	Q7Z6K1
Entrez:	168451

Family

Belongs to:

No superfamily

Alternative Names

DKFZp313O1132; THAP domain containing 5; THAP domain-containing protein 5

Molecular Weight

Mass (kDA):
45.416 kDA

Genomic Context


Human

Location:	7q31.1
Sequence:	7; NC_000007.14 (108562132..108569768, complement)

Tissue Specificity

Detected in heart (PubMed:19502560, PubMed:21195082). Detected in brain and muscle (at protein level) (PubMed:19502560). Highly expressed in the heart. Also found in brain and skeletal muscle (PubMed:19502560, PubMed:21195082).

Subcellular Localizations

Nucleus.

Diseases

Coronary Artery Disease
Myocardial Infarction
Heart Diseases
Infarction
Myocardial Reperfusion Injury
Skin Neoplasms

Melanoma

Pathways

Cell Death
Cell Cycle
Cell Cycle Arrest

PTMs

Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THAP5

References

PMID: 19502560 by Balakrishnan M.P., et al. THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.

PMID: 21110952 by Balakrishnan M.P., et al. THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death.