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- Table of Contents
Facts about Telomere length regulation protein TEL2 homolog.
The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Along with the TTT complex and HSP90 may participate in the correct folding of newly synthesized PIKKs.
Human | |
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Gene Name: | TELO2 |
Uniprot: | Q9Y4R8 |
Entrez: | 9894 |
Belongs to: |
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TEL2 family |
CLK2; DKFZp434A073; EC 1.1.1.27; EC 2.7.11.1; hCLK2; KIAA0683FLJ10924; Protein clk-2 homolog; TEL2; TEL2, telomere maintenance 2, homolog (S. cerevisiae); telomere length regulation protein TEL2 homolog
Mass (kDA):
91.747 kDA
Human | |
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Location: | 16p13.3 |
Sequence: | 16; NC_000016.10 (1493345..1510459) |
Cytoplasm. Membrane. Nucleus. Chromosome, telomere.
PMID: 12670948 by Jiang N., et al. Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation.
PMID: 20810650 by Hurov K.E., et al. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.