F-box-like/WD repeat-containing protein TBL1Y (TBL1Y)

F-box-like protein involved in the recruitment of this ubiquitin/19S proteasome complex to atomic receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors.

Probably acts as integral part of corepressor complexes that mediates the recruitment of the 19S proteasome complex, resulting in the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity). .