LRSAM1 Antibodies

AND LRSAM1 ELISA kits, LRSAM1 Proteins

Many biological assays use antibodies to detect LRSAM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRSAM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRSAM1 antibodies...

We validate the specificity of these antibodies to LRSAM1 by testing them on tissues known to express LRSAM1 positively and negatively. Browse below to find the LRSAM1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: FAM104B

LRSAM1 Infographic by Boster Bio

All LRSAM1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LRSAM1 Antibody

Human, Mouse, Rat

$405
Cat # A06223
100ul

LRSAM1 (NM_001005373) Human Recombinant Protein

$813
Cat # PROTQ6UWE0
20 µg

LRSAM1 (NM_138361) Human Over-expression Lysate

Human

$628
Cat # LS090678
100 µg

LRSAM1 Overview

Facts about E3 ubiquitin-protein ligase LRSAM1.

LRSAM1 3D structure. Source: alphafold

E3 ubiquitin-protein ligase LRSAM1 (LRSAM1)

E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the capability of TSG101 to form endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein which defends the cytoplasm from invasive pathogens (PubMed:23245322).

Localizes to several intracellular bacterial pathogens and creates the bacteria- related ubiquitin signal resulting in autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098). .

Gene Information

Human
Gene Name:	LRSAM1
Uniprot:	Q6UWE0
Entrez:	90678

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.2.-; FLJ31641; hTAL; leucine rich repeat and sterile alpha motif containing 1; Leucine-rich repeat and sterile alpha motif-containing protein 1; RIFLE; TALE3 ubiquitin-protein ligase LRSAM1; Tsg101-associated ligase

Molecular Weight

Mass (kDA):
83.594 kDA

Genomic Context


Human

Location:	9q33.3-q34.11
Sequence:	9; NC_000009.12 (127451486..127503501)

Tissue Specificity

Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.

Subcellular Localizations

Cytoplasm. Displays a punctuate distribution and localizes to a submembranal ring (PubMed:15256501). Localizes to intracellular bacterial pathogens (PubMed:23245322).