TAS2R46 Antibodies

AND TAS2R46 ELISA kits, TAS2R46 Proteins

Many biological assays use antibodies to detect TAS2R46, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TAS2R46 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TAS2R46 antibodies...

We validate the specificity of these antibodies to TAS2R46 by testing them on tissues known to express TAS2R46 positively and negatively. Browse below to find the TAS2R46 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TAS2R46 Infographic by Boster Bio

All TAS2R46 Products

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Specificity

Applications

Price

Anti-T2R46 TAS2R46 Antibody

Human

ELISA, WB

$380
Cat # A12897
100ul

TAS2R46 (NM_176887) Human Over-expression Lysate

Human

$628
Cat # LS259292
100 µg

TAS2R46 Overview

Facts about Taste receptor type 2 member 46.

TAS2R46 3D structure. Source: alphafold

Taste receptor type 2 member 46 (TAS2R46)

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content.

The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).

Gene Information

Human
Gene Name:	TAS2R46
Uniprot:	P59540
Entrez:	259292

Family

Belongs to:

G-protein coupled receptor T2R family

Alternative Names

MGC134865; T2R54T2R46Taste receptor type 2 member 54; taste receptor type 2 member 46; taste receptor, type 2, member 46

Molecular Weight

Mass (kDA):
35.523 kDA

Genomic Context


Human

Location:	12p13.2
Sequence:	12; NC_000012.12 (11061365..11062294, complement)

Tissue Specificity

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed on ciliated airway epithelium.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. In airway epithelial cells, localizes to motile cilia.

PTMs

Glycoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAS2R46

References

PMID: 12584440 by Conte C., et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.

PMID: 15496549 by Fischer A., et al. Evolution of bitter taste receptors in humans and apes.