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- Table of Contents
Facts about Taste receptor type 2 member 31.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the sulfonyl amide sweeteners saccharin and acesulfame K.
Human | |
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Gene Name: | TAS2R31 |
Uniprot: | P59538 |
Entrez: | 259290 |
Belongs to: |
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G-protein coupled receptor T2R family |
Taste receptor type 2 member 31
Mass (kDA):
35.278 kDA
Human | |
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Location: | 12p13.2 |
Sequence: | 12; NC_000012.12 (11030387..11031407, complement) |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Membrane; Multi-pass membrane protein.
PMID: 12379855 by Bufe B., et al. The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides.
PMID: 12584440 by Conte C., et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.