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TADA2A Antibodies
AND TADA2A ELISA kits, TADA2A Proteins
Many biological assays use antibodies to detect TADA2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TADA2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TADA2A antibodies...
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TADA2A Infographic by Boster Bio
All TADA2A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1650
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1650
1 kit, containing one 96-well plate and all necessary reagents
TADA2A Overview
Facts about Transcriptional adapter 2-alpha.
Transcriptional adapter 2-alpha (TADA2A)
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of several acidic activation domains, which activate transcription from a remote site (By similarity).
Binds dinucleosomes, probably in the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.
Gene Information
| Human | |
|---|---|
| Gene Name: | TADA2A |
| Uniprot: | O75478 |
| Entrez: | 6871 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ADA2AFLJ12705; ADA2-like protein; hADA2; TADA2LADA2; transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 (ADA2 homolog, yeast)-like; transcriptional adaptor 2 alpha; transcriptional adaptor 2A
Molecular Weight
Mass (kDA):
51.506 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (37406877..37479725) |
Subcellular Localizations
Nucleus. Chromosome.
Diseases
- Immunologic Deficiency Syndromes
- Malignant Neoplasms
- Severe Combined Immunodeficiency
- Congenital Combined Immunodeficiency
- Pancreatic Atrophy
- Hypoxia
- Malignant Neoplasm Of Lung
- Inflammatory Response
- Hypokinesia
- Acute Erythroblastic Leukemia
- Neoplasms
- Lupus Erythematosus, Systemic
Interacting Proteins
- AATF
- C1orf109
- CCDC134
- CDCA7L
- EIF4E2
- FARS2
- GPSM3
- HGS
- KLC4
- KLHL38
Pathways
- Chromatin Remodeling
- Protein Folding
- Tissue Development
- Cell Cycle
- Histone Acetylation
- Glycosylation
- Tissue Homeostasis
- Cell Cycle Arrest
PTMs
- Acetylation
Research Areas
- Cell Cycle and Replication
- mTOR Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TADA2A
bosterbio.com/bosterbio-gene-info-cards/TADA2A
References
PMID: 8552087 by Candau R., et al. Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.
PMID: 9674425 by Ogryzko V.V., et al. Histone-like TAFs within the PCAF histone acetylase complex.