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- Table of Contents
Facts about Mitochondria-eating protein.
Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (called MIV), which engulf and degrade unhealthy mitochondria by amassing lysosomes. May have a role in spermatogenesis, especially in cell differentiation from late elongate spermatids to mature spermatozoa (By similarity).
Mouse | |
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Gene Name: | Spata18 |
Uniprot: | Q0P557 |
Entrez: | 73472 |
Belongs to: |
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MIEAP family |
FLJ32906; Mieap; mitochondria-eating protein; spermatogenesis associated 18 homolog (rat); Spermatogenesis-associated protein 18; SPETEX1
Mass (kDA):
60.398 kDA
Mouse | |
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Location: | 5|5 C3.3 |
Sequence: | 5; |
In testis, expressed primarily in spermatids.
PMID: 21300779 by Bornstein C., et al. SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63.