Spermine oxidase Antibodies

AND SMOX ELISA kits, Spermine oxidase Proteins

Many biological assays use antibodies to detect Spermine oxidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spermine oxidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spermine oxidase antibodies...

We validate the specificity of these antibodies to Spermine oxidase by testing them on tissues known to express SMOX positively and negatively. Browse below to find the SMOX antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMOX Infographic by Boster Bio

All SMOX Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SMOX Antibody Picoband®

1 Q&As

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05519-1
100 μg/vial

SMOX (NM_175839) Human Over-expression Lysate

Human

$960
Cat # LS054498
100 µg

Anti-SMOX Antibody Picoband®

+11

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05519-2
100 μg/vial

SMOX Overview

Facts about Spermine oxidase.

SMOX 3D structure. Source: alphafold

Spermine oxidase (SMOX)

Flavoenzyme that catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions.

Plays an essential role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production through aldehyde dehydrogenase conversion of 3-amino-propanal.

Gene Information

Human
Gene Name:	SMOX
Uniprot:	Q9NWM0
Entrez:	54498

Family

Belongs to:

flavin monoamine oxidase family

Alternative Names

C20orf16; chromosome 20 open reading frame 16; EC 1.5.3.16; flavin containing amine oxidase; flavin-containing spermine oxidase; FLJ20746; MGC1010; PAO; PAO-1; PAOH1; Polyamine oxidase 1; putative cyclin G1 interacting protein; SMOdJ779E11.1; spermine oxidase

Molecular Weight

Mass (kDA):
61.819 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (4148779..4187747)

Tissue Specificity

Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line.

Subcellular Localizations

[Isoform 1]: Cytoplasm. Nucleus.; [Isoform 4]: Cytoplasm. Nucleus.; [Isoform 6]: Cytoplasm. Nucleus.

Diseases

Pre-eclampsia
Malignant Neoplasms
Cancer Patients And Suicide And Depression
Embryonal Carcinoma
Pediatric Neoplasm
Mood Disorders
Oncogene Deregulation
Neurodegenerative Disorders
Parkinson Disease
Patient Dependence On
Neoplasms
Neuroblastoma

Muscle Injury
Cell Transformation, Neoplastic
Anxiety Disorders
Autoimmune Diseases
Diabetes Mellitus
Dystrophy

Pathways

Methylation
Cell Proliferation
Cell Death
Axon Guidance
Muscle Contraction
Germ Cell Proliferation
Pathogenesis
Neuroblast Proliferation

Spermatogenesis
Oncogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMOX

References

PMID: 11454677 by Wang Y., et al. Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure.

PMID: 12398765 by Murray-Stewart T., et al. Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics.