Spermine oxidase Antibodies

Spermine oxidase (SMOX)

Flavoenzyme that catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions.

Plays an essential role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production through aldehyde dehydrogenase conversion of 3-amino-propanal.

Gene Information

Human
Gene Name:	SMOX
Uniprot:	Q9NWM0
Entrez:	54498

Family

Belongs to:
flavin monoamine oxidase family

Alternative Names

C20orf16; chromosome 20 open reading frame 16; EC 1.5.3.16; flavin containing amine oxidase; flavin-containing spermine oxidase; FLJ20746; MGC1010; PAO; PAO-1; PAOH1; Polyamine oxidase 1; putative cyclin G1 interacting protein; SMOdJ779E11.1; spermine oxidase

Molecular Weight

Mass (kDA):
61.819 kDA

Genomic Context

Human
Location:	20p13
Sequence:	20; NC_000020.11 (4148779..4187747)

Tissue Specificity

Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line.

Subcellular Localizations

[Isoform 1]: Cytoplasm. Nucleus.; [Isoform 4]: Cytoplasm. Nucleus.; [Isoform 6]: Cytoplasm. Nucleus.

Diseases

• Pre-eclampsia
• Malignant Neoplasms
• Cancer Patients And Suicide And Depression
• Embryonal Carcinoma
• Pediatric Neoplasm
• Mood Disorders
• Oncogene Deregulation
• Neurodegenerative Disorders
• Parkinson Disease
• Patient Dependence On
• Neoplasms
• Neuroblastoma

• Muscle Injury
• Cell Transformation, Neoplastic
• Anxiety Disorders
• Autoimmune Diseases
• Diabetes Mellitus
• Dystrophy

Pathways

• Methylation
• Cell Proliferation
• Cell Death
• Axon Guidance
• Muscle Contraction
• Germ Cell Proliferation
• Pathogenesis
• Neuroblast Proliferation

• Spermatogenesis
• Oncogenesis

PTMs

• Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMOX

Best Uses Of The SMOX Marker

This article will introduce you to immunofluorescence. IHC, ICC and immunofluorescence are all methods that can be used for identifying the SMOX marker inside your cells. Learn how to use these methods in your own research. There are some key differences between the two methods, and you can find out which ones are better for your research.

Anti-SMOX Antibody Picoband (tm)

This ELISA test kit is designed for the detection of biomarkers related to cancer, neurosciences and inflammation. It can detect biomarkers as low as a picogram. Researchers around the world are encouraged use this immunological agent to discover new biomarkers. Sanbio is the company’s distributor in BeNeLux. You can find more information about Boster Bio on its website.

The ELISA method used to detect the antibody is also called Bo Si Te Sheng Wu Ji Shu. Boster Bio is the inventor of this method, and has been working on it for over 20 years. The Chinese name for the antibody is Jin Guan Lai Zi Zhong Guo. It is also known as Bo Si Te Sheng Wu Ji Shu in the West, or Boster Bio.

IHC

If you're a biomedical researcher, you'll appreciate the IHC options offered by Boster Bio. These services allow you to validate all Boster Bio antibodies, including those used in IHC. You can purchase antibodies for IHC and WB, as well as ELISA and FC. Unlike many other lab supplies, Boster offers a free secondary antibody with every purchase. They will help you answer any questions that you might have.

Boster Bio offers immunohistochemistry as a service. This allows for the transfer of research assays into diagnostic tests. You will also find helpful troubleshooting suggestions in the IHC Guide. These tips cover common problems like weak staining (background staining), and non-specific stained. This guide also gives an overview of the immunohistochemistry resources available. Boster Bio has selected some of the most important protocols and methods to help you with your IHC research.

Steven Xia was a renowned histologist who founded Boster Bio in 1993. The company has over 12,000 validated antibodies for IHC and ELISA. Boster antibodies have been validated by IHC, WB, Flow and using panels from 250 tissues. The company stands behind their products by offering a Boster Quality Guarantee, which ensures their products will work as described.

IHC is a valuable tool for detecting protein patterns in biological samples. In this technique, primary antibodies bind to proteins of interest, and secondary antibodies bind to these antibodies. This allows researchers more information about a specimen and can produce more reliable and relevant results. With this technology, Boster Bio makes it easier to identify specific proteins with minimal fuss. This innovative technique allows you to quickly identify a protein and then use it for understanding the underlying biology.

ICC

SMOX, a protein that is part of the immune system, is known as a component. It is a protein that is found in the immune system. It plays a crucial role in determining vaccine effectiveness. It is widely used in animal studies. Boster Bio offers several antisera which can be used to detect SMOX. These antibodies have high affinity and specificity. Boster also awards product credits to the first reviewer who reviews a product. This program is open all scientists around the world.

Immunofluorescence

SMOX is an antibody that can be used for protein localization in situ and to confirm the proper fractionation cell lysates. It is compatible both with quantitative and qualitative immunofluorescence techniques. Boster Bio's SMOX is a robust immunofluorescence assay. It can be used to detect a wide range of proteins, including cancer cells, glial cells, astrocytes, and endothelial cells.