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- Table of Contents
Facts about Sodium-dependent neutral amino acid transporter B(0)AT2.
Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons.
Human | |
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Gene Name: | SLC6A15 |
Uniprot: | Q9H2J7 |
Entrez: | 55117 |
Belongs to: |
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sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family |
B0AT2; DKFZp761I0921; FLJ10316; homolog of rat orphan transporter v7-3; hv7-3; MGC87066; NTT73orphan sodium- and chloride-dependent neurotransmitter transporter NTT73; orphan transporter v7-3; SBAT1; Sodium- and chloride-dependent neurotransmitter transporter NTT73; sodium/chloride dependent neurotransmitter transporter Homo sapiens orphanneurotransmitter transporter NTT7; Sodium-coupled branched-chain amino-acid transporter 1; solute carrier family 6 (neurotransmitter transporter), member 15; solute carrier family 6 (neutral amino acid transporter), member 15; Solute carrier family 6 member 1
Mass (kDA):
81.836 kDA
Human | |
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Location: | 12q21.31 |
Sequence: | 12; NC_000012.12 (84859491..84912829, complement) |
Almost exclusively expressed in the brain.
Membrane; Multi-pass membrane protein.
PMID: 11112352 by Farmer M.K., et al. Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family.
PMID: 16226721 by Takanaga H., et al. Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain.