SEPSECS Antibodies

AND SEPSECS ELISA kits, SEPSECS Proteins

Many biological assays use antibodies to detect SEPSECS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEPSECS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEPSECS antibodies...

We validate the specificity of these antibodies to SEPSECS by testing them on tissues known to express SEPSECS positively and negatively. Browse below to find the SEPSECS antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEPSECS Infographic by Boster Bio

All SEPSECS Products

Product

Figures

Specificity

Applications

Price

Anti-SEPSECS Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05769
100ul

Mouse Sepsecs Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ6P6M7
Starting from 4ug

Human SEPSECS Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9HD40
Starting from 20ug

SEPSECS Overview

Facts about O-phosphoseryl-tRNA(Sec) selenium transferase.

SEPSECS 3D structure. Source: alphafold

O-phosphoseryl-tRNA(Sec) selenium transferase (SEPSECS)

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. .

Gene Information

Human
Gene Name:	SEPSECS
Uniprot:	Q9HD40
Entrez:	51091

Family

Belongs to:

SepSecS family

Alternative Names

EC 2.9.1.2; EC 2.9.1.n1; Liver-pancreas antigen; LPDKFZp434B1417; MGC161491; O-phosphoseryl-tRNA(Sec) selenium transferase; Sec synthase; Selenocysteine synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; SepSecS; Sep-tRNA:Sec-tRNA synthase; SLA/LP autoantigen; SLA/LP; SLA-p35; SLAUGA suppressor tRNA-associated protein; Soluble liver antigen; soluble liver antigen/liver pancreas antigen; tRNA(Ser/Sec)-associated antigenic protein; TRNP48

Molecular Weight

Mass (kDA):
55.726 kDA

Genomic Context


Human

Location:	4p15.2
Sequence:	4; NC_000004.12 (25120014..25160546, complement)

Tissue Specificity

Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.

Subcellular Localizations

Cytoplasm.

Diseases

Autoimmune Reaction
Hepatitis, Autoimmune
Hepatitis
Crohn Disease
Chimera Disorder
Atrophy

Hypokinesia

Pathways

Translation

PTMs

Phosphorylation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEPSECS

References

PMID: 10801173 by Wies I., et al. Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis.

PMID: 10931155 by Costa M., et al. Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients withtype-1 autoimmune hepatitis.