Synaptopodin-2 Antibodies

AND Synpo2 ELISA kits, Synaptopodin-2 Proteins

Many biological assays use antibodies to detect Synaptopodin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptopodin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptopodin-2 antibodies...

We validate the specificity of these antibodies to Synaptopodin-2 by testing them on tissues known to express Synpo2 positively and negatively. Browse below to find the Synpo2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Synpo2 Infographic by Boster Bio

All Synpo2 Products

Product

Figures

Specificity

Applications

Price

Anti-Synaptopodin-2 SYNPO2 Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A07616
0.1 mg

Anti-SYNPO2 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07616-1
100 µg/vial

Synpo2 Overview

Facts about Synaptopodin-2.

Synaptopodin-2 (Synpo2)

Has an actin-binding and actin-bundling action (PubMed:11673475). Can induce the formation of F-actin networks.

In the sarcomeric Z lines is proposed to serve as adapter protein that links nascent myofibers to the sarcolemma through ZYX and may play a role in early assembly and stabilization of the Z lines. May play a role in chaperone- assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical strain; can connect the client-processing CASA chaperone machines to a membrane- tethering and fusion complex providing autophagosome membranes.

Gene Information

Mouse
Gene Name:	Synpo2
Uniprot:	Q91YE8
Entrez:	118449

Family

Belongs to:

synaptopodin family

Alternative Names

synaptopodin-2; synaptopodin 2

Molecular Weight

Mass (kDA):
116.527 kDA

Genomic Context


Mouse

Location:	3\|3 G1
Sequence:	3;

Tissue Specificity

Expressed in skeletal muscle, heart, colon, stomach, uterus and lung. Expression is restricted to muscle cell layers in colon, uterus and stomach.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Urinary Bladder
Cell Invasion
Neoplasm Invasiveness
Bladder Neoplasm
Carcinoma
Myopathy
Embryonal Carcinoma

Non-neoplastic Disorder
Colonic Neoplasms
Seminoma
Epispadias
Malignant Tumor Of Colon
Neuromuscular Diseases
Muscular Dystrophy, Duchenne

Pathways

Localization
Nuclear Import
Nuclear Export
Methylation
Cell Migration
Cell Motility
Transport
Cell Proliferation
Neural Crest Cell Migration
Protein Targeting
Neuron Differentiation

Nuclear Transport
Myotube Differentiation
System Development
Cell Growth
Rna Interference
Cell-cell Adhesion

PTMs

Methylation
Phosphorylation

Demethylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Synpo2

References

PMID: 11673475 by Weins A., et al. Differentiation and stress-dependent nuclear-cytoplasmic redistribution of myopodin, a novel actin bundling protein.

PMID: 15883195 by Faul C., et al. Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.