SUSD4 Antibodies

AND SUSD4 ELISA kits, SUSD4 Proteins

Many biological assays use antibodies to detect SUSD4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUSD4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUSD4 antibodies...

We validate the specificity of these antibodies to SUSD4 by testing them on tissues known to express SUSD4 positively and negatively. Browse below to find the SUSD4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SUSD4 Infographic by Boster Bio

All SUSD4 Products

Product

Figures

Specificity

Applications

Price

SUSD4 (NM_001037175) Human Recombinant Protein

$1249
Cat # PROTQ5VX71
20 µg

SUSD4 (NM_017982) Human Over-expression Lysate

Human

$960
Cat # LS055061
100 µg

SUSD4 Overview

Facts about Sushi domain-containing protein 4.

SUSD4 3D structure. Source: alphafold

Sushi domain-containing protein 4 (SUSD4)

Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b through both the classical and alternative complement pathways.

Gene Information

Human
Gene Name:	SUSD4
Uniprot:	Q5VX71
Entrez:	55061

Family

Belongs to:

No superfamily

Alternative Names

FLJ10052; PRO222; sushi domain containing 4; sushi domain-containing protein 4; YHGM196

Molecular Weight

Mass (kDA):
53.778 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (223220826..223365271, complement)

Subcellular Localizations

[Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.

Diseases

Limb Deformities, Congenital
Autistic Disorder
Congenital Abnormality
Fryns Syndrome
Diaphragmatic Hernia

Pathways

Complement Activation
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUSD4

References

PMID: 23482636 by Holmquist E., et al. Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase.