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- Table of Contents
Facts about Stathmin-2.
In the developing brain, negatively regulates the rate of exit from multipolar phase and retards radial migration from the ventricular zone (By similarity). .
Human | |
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Gene Name: | STMN2 |
Uniprot: | Q93045 |
Entrez: | 11075 |
Belongs to: |
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stathmin family |
FLJ34868; FLJ50995; neuron-specific growth-associated protein; Protein SCG10; SCG10; SCG10neuronal growth-associated protein (silencer element); SCGN10; SCGN10stathmin-2; Stathmin2; Stathmin-2; stathmin-like 2; STMN2; superior cervical ganglia, neural specific 10; Superior cervical ganglion-10 protein
Mass (kDA):
20.828 kDA
Human | |
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Location: | 8q21.13 |
Sequence: | 8; NC_000008.11 (79611117..79666162) |
Neuron specific.
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamel
PMID: 8622778 by Okazaki T., et al. SCG10, a neuron-specific growth-associated protein in Alzheimer's disease.
PMID: 15561718 by Gocke C.B., et al. Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates.