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- Table of Contents
Facts about SH3 and cysteine-rich domain-containing protein 3.
Probably works via its effects on muscle calcium channels. Increases CACNA1S channel activity, as well as its role in improving the expression of CACNA1S at the cell membrane (PubMed:27621462).
Mouse | |
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Gene Name: | Stac3 |
Uniprot: | Q8BZ71 |
Entrez: | 237611 |
Belongs to: |
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No superfamily |
MGC2793; SH3 and cysteine rich domain 3; SH3 and cysteine-rich domain-containing protein 3
Mass (kDA):
41 kDA
Mouse | |
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Location: | 10|10 D3 |
Sequence: | 10; |
Dected in skeletal muscle, including soleus, extensor digitorum longus, tibialis anterior, quadriceps and gastronemicus. Detected in tongue.
PMID: 23626854 by Reinholt B.M., et al. Stac3 is a novel regulator of skeletal muscle development in mice.
PMID: 23818578 by Nelson B.R., et al. Skeletal muscle-specific T-tubule protein STAC3 mediates voltage- induced Ca2+ release and contractility.