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- Table of Contents
Facts about Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3.
Involved in the biosynthesis of ganglioside GD1A from GM1B.
Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids.ST6GalNAcIII prefers glycolipids to glycoproteins. .
Mouse | |
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Gene Name: | St6galnac3 |
Uniprot: | Q9WUV2 |
Entrez: | 20447 |
Belongs to: |
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glycosyltransferase 29 family |
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase III; EC 2.4.99.-; EC 2.4.99.7; FLJ13669; FLJ27239; GalNAc alpha-2,6-sialyltransferase III; PRO7177; sialyltransferase 7((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminidealpha-2,6-sialyltransferase) C; Sialyltransferase 7C; SIAT7C; SIAT7-C; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltran; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 3; ST6G
Mass (kDA):
35.414 kDA
Mouse | |
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Location: | 3|3 H3 |
Sequence: | 3; |
High expression in brain, lung and heart and to a lesser extent in kidney, mammary gland, spleen, testis and thymus.
PMID: 10207017 by Lee Y.-C., et al. Molecular cloning and functional expression of two members of mouse NeuAc-alpha-2,3Gal-beta-1,3GalNAc GalNAc-alpha2,6-sialyltransferase family, ST6GalNAc III and IV.