Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (St6galnac3)

Involved in the biosynthesis of ganglioside GD1A from GM1B.

Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids.

ST6GalNAcIII prefers glycolipids to glycoproteins. .