ST8SIA2 Antibodies

AND ST8SIA2 ELISA kits, ST8SIA2 Proteins

Many biological assays use antibodies to detect ST8SIA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ST8SIA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ST8SIA2 antibodies...

We validate the specificity of these antibodies to ST8SIA2 by testing them on tissues known to express ST8SIA2 positively and negatively. Browse below to find the ST8SIA2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ST8SIA2 Infographic by Boster Bio

All ST8SIA2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Alpha-2,8-sialyltransferase 8B ST8SIA2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A05894
100ul

ST8SIA2 (NM_006011) Human Over-expression Lysate

Human

$628
Cat # LS008128
100 µg

Anti-ST8SIA2 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A05894-1
100 µg/vial

ST8SIA2 Overview

Facts about Alpha-2,8-sialyltransferase 8B.

ST8SIA2 3D structure. Source: alphafold

Alpha-2,8-sialyltransferase 8B (ST8SIA2)

May transfer sialic acid via alpha-2,8-linkages to the alpha-2,3-connected and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and might be involved in PSA (polysialic acid) expression. .

Gene Information

Human
Gene Name:	ST8SIA2
Uniprot:	Q92186
Entrez:	8128

Family

Belongs to:

glycosyltransferase 29 family

Alternative Names

alpha-2,8-sialyltransferase 8B 1; alpha-2,8-sialyltransferase 8B; EC 2.4.99; EC 2.4.99.-; HsT19690; MGC116854; MGC116857; sialyltransferase 8 (alpha-2, 8-sialytransferase) B; Sialyltransferase 8B; Sialyltransferase X; Sialytransferase St8Sia II; SIAT8B; SIAT8-B; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; ST8SIA2; ST8SiaII; ST8SIA-II; STX; STXST8SiaII

Molecular Weight

Mass (kDA):
42.43 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (92393881..92468728)

Tissue Specificity

Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Bipolar Disorder
Schizophrenia
Tissue Adhesions
Nervousness
Autistic Disorder
Schizoaffective Disorder
Cardiac Arrhythmia
Mood Disorders
Teratocarcinoma
Developmental Delay (disorder)
Developmental Disabilities

Psychotic Disorders
Epilepsy
Mental Disorders
Major Depressive Disorder
Cardiomyopathies
Hypoplasia

Pathways

Cell Adhesion
Regeneration
Brain Development
Glycosylation
Neuron Differentiation
Cell-cell Adhesion

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ST8SIA2

References

PMID: 7559389 by Scheidegger E.P., et al. A human STX cDNA confers polysialic acid expression in mammalian cells.

PMID: 9054414 by Angata K., et al. Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST.