SSU72 Antibodies

AND SSU72 ELISA kits, SSU72 Proteins

Many biological assays use antibodies to detect SSU72, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SSU72 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SSU72 antibodies...

We validate the specificity of these antibodies to SSU72 by testing them on tissues known to express SSU72 positively and negatively. Browse below to find the SSU72 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SSU72 Infographic by Boster Bio

All SSU72 Products

Product

Figures

Specificity

Applications

Price

SSU72 (NM_014188) Human Recombinant Protein

$1249
Cat # PROTQ9NP77
20 µg

Anti-SSU72 Mouse Monoclonal Antibody [Clone ID: OTI5A1]

Human, Mouse, Rat

IHC, WB

$523
Cat # M06296
100 µl

SSU72 (NM_014188) Human Over-expression Lysate

Human

$628
Cat # LS029101
100 µg

SSU72 Overview

Facts about RNA polymerase II subunit A C-terminal domain phosphatase SSU72.

SSU72 3D structure. Source: alphafold

RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (SSU72)

Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK. .

Gene Information

Human
Gene Name:	SSU72
Uniprot:	Q9NP77
Entrez:	29101

Family

Belongs to:

SSU72 phosphatase family

Alternative Names

CTD phosphatase SSU72; EC 3.1.3.16; FLJ13048; HSPC182; PNAS-120; RNA polymerase II subunit A C-terminal domain phosphatase SSU72; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)

Molecular Weight

Mass (kDA):
22.574 kDA

Genomic Context


Human

Location:	1p36.33
Sequence:	1; NC_000001.11 (1541673..1574863, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Predominantly in the cytosol.

Diseases

Nervousness
Learning Disorders
Neoplasms
Impairment (finding)
Neurodegenerative Disorders
Memory Impairment
Impaired Cognition
Osteoporosis
Alzheimer's Disease

Punctate Inner Choroidopathy
Cold Intolerance
Dysequilibrium Syndrome

Interacting Proteins

RAD21
STAG2
SYMPK

Pathways

Gene Looping
Mrna Processing
Rna Processing
Mrna 3'-end Processing
Mitosis
Immune Response
Snorna Transcription
Localization
Termination Of Rna Polymerase Ii Transcription
Mrna Cleavage
Methylation
System Development
Mrna Transcription

Cell Cycle
Sister Chromatid Cohesion
Nervous System Development
S Phase
Cell Differentiation
Cell Growth
Meiosis

PTMs

Phosphorylation
Dephosphorylation

Cleavage
Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SSU72

References

PMID: 15659578 by St Pierre B., et al. Conserved and specific functions of mammalian ssu72.

PMID: 29158257 by Bratkowski M., et al. Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.