Protein SSXT Antibodies

AND SS18 ELISA kits, Protein SSXT Proteins

Many biological assays use antibodies to detect Protein SSXT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein SSXT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein SSXT antibodies...

We validate the specificity of these antibodies to Protein SSXT by testing them on tissues known to express SS18 positively and negatively. Browse below to find the SS18 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: ST14

SS18 Infographic by Boster Bio

All SS18 Products

Product

Figures

Specificity

Applications

Price

Anti-SYT SS18 Antibody

Human, Mouse, Rat

$399
Cat # A03947
100μl

Anti-SSXT SS18 Antibody

6 Q&As

Human, Mouse, Rat

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A30497
100ul

SSXT Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1822
1 kit, containing one 96-well plate and all necessary reagents

Anti-SYT (A7) SS18 Antibody

Human, Mouse, Rat

IHC

$405
Cat # A03947-1
100ul

Anti-SS18 Mouse Monoclonal Antibody [Clone ID: OTI4F11]

Human, Mouse, Rat

$523
Cat # M03947
100 µl

SS18 (NM_001007559) Human Over-expression Lysate

Human

$960
Cat # LS006760
100 µg

SS18 Overview

Facts about Protein SSXT.

SS18 3D structure. Source: alphafold

Protein SSXT (SS18)

Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation.

Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic actions, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).

Gene Information

Human
Gene Name:	SS18
Uniprot:	Q15532
Entrez:	6760

Family

Belongs to:

SS18 family

Alternative Names

MGC116875; Protein SYT; SSXTsynovial sarcoma, translocated to X chromosome; Synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation, chromosome 18; SYTprotein SSXT

Molecular Weight

Mass (kDA):
45.929 kDA

Genomic Context


Human

Location:	18q11.2
Sequence:	18; NC_000018.10 (26016253..26091217, complement)

Tissue Specificity

Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.

Subcellular Localizations

Nucleus.

Diseases

Synovial Sarcoma
Sarcoma
Neoplasms
Chromosomal Translocation
Soft Tissue Neoplasms
Malignant Paraganglionic Neoplasm
Malignant Neoplasms
Neoplasm Metastasis
Neoplasms, Fibrous Tissue
Bone Neoplasms
Tissue Adhesions
Carcinoma

Solitary Fibrous Tumor
Neoplasm Recurrence, Local
Malignant Peripheral Nerve Sheath Tumor
Epithelioid Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Primary Synovial Sarcoma

Interacting Proteins

ATF2

Pathways

Reverse Transcription
Localization
Interphase
Chromatin Remodeling
Cell Adhesion
Metaphase
Cell Proliferation
Mitosis
Pathogenesis
Cell Migration
Dna Repair
Dna Methylation

Rna Splicing
Methylation
Cell Division
Chorio-allantoic Fusion
Translation
Regulation Of Cell Migration
Oncogenesis

PTMs

Methylation

Biotinylation

Ubiquitination

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SS18

References

PMID: 7951320 by Clark J., et al. Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma.

PMID: 11368913 by Brodin B., et al. Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression.