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- Table of Contents
Facts about Sperm flagellar protein 2.
Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 into the manchette, suggesting function as an adapter for dynein-mediated protein transfer during spermatogenesis.
Rat | |
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Gene Name: | Spef2 |
Uniprot: | Q9R095 |
Entrez: | 64555 |
Belongs to: |
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No superfamily |
cancer/testis antigen 122; CT122; FLJ23164; FLJ23577; FLJ25395; KIAA1770; KPL2MGC102842; Protein KPL2; sperm flagellar 2; sperm flagellar protein 2
Mass (kDA):
208.159 kDA
Rat | |
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Location: | 2q16 |
Sequence: | 2; |
Predominantly expressed in ciliated tissues such as lung, trachea, testis, brain, and at lower levle in kidney and spleen.
PMID: 10100999 by Ostrowski L.E., et al. Cloning and characterization of KPL2, a novel gene induced during ciliogenesis of tracheal epithelial cells.