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- Table of Contents
Facts about Spartin.
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Human | |
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Gene Name: | SPART |
Uniprot: | Q8N0X7 |
Entrez: | 23111 |
Belongs to: |
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No superfamily |
Spartin
Mass (kDA):
72.833 kDA
Human | |
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Location: | 13q13.3 |
Sequence: | 13; NC_000013.11 (36301638..36370180, complement) |
Ubiquitously expressed, with highest levels of expression detected in adipose tissue.
Cytoplasm. Midbody. Transiently associated with endosomes (PubMed:19580544). Colocalized with IST1 to the ends of Flemming bodies during cytokinesis (PubMed:20719964).
PMID: 12134148 by Patel H., et al. SPG20 is mutated in Troyer syndrome, an hereditary spastic paraplegia.
PMID: 12676568 by Ciccarelli F.D., et al. The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia.