Cullin-9 Antibodies

AND CUL9 ELISA kits, Cullin-9 Proteins

Many biological assays use antibodies to detect Cullin-9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cullin-9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cullin-9 antibodies...

We validate the specificity of these antibodies to Cullin-9 by testing them on tissues known to express CUL9 positively and negatively. Browse below to find the CUL9 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CUL9 Infographic by Boster Bio

All CUL9 Products

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Product

Figures

Specificity

Applications

Price

Anti-PARC CUL9 Antibody

5 Q&As

Human

IHC, WB

$629
Cat # A08481
100uL

Anti-PARC CUL9 Antibody

Human, Mouse

ELISA, IF, ICC, WB

$449
Cat # A08481-1
0.1 mg

PARC (CUL9) (NM_015089) Human Over-expression Lysate

Human

$960
Cat # LS023113
100 µg

CUL9 Overview

Facts about Cullin-9.

CUL9 3D structure. Source: alphafold

Cullin-9 (CUL9)

Core element of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, resulting in prevent ubiquitination of BIRC5 (PubMed:24793696).

Cytoplasmic anchor protein in p53/TP53- related protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).

Gene Information

Human
Gene Name:	CUL9
Uniprot:	Q8IWT3
Entrez:	23113

Family

Belongs to:

cullin family

Alternative Names

CUL-9; cullin 9; cullin-9; DKFZp686G1042; H7AP1DKFZp686P2024; p53-associated parkin-like cytoplasmic protein; PARCKIAA0708; parkin-like cytoplasmic p53 binding protein; RP3-330M21.2; UbcH7-associated protein 1

Molecular Weight

Mass (kDA):
281.229 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (43182170..43224587)

Tissue Specificity

Ubiquitously expressed in all tissues with highest expression in testis brain and kidney.

Subcellular Localizations

Cytoplasm.

Diseases

Leukemogenesis
Neoplasm Metastasis
Neoplasms
Lymphoma
Sarcoma
Carcinogenesis

Interacting Proteins

TP53

PTMs

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CUL9

References

PMID: 12526791 by Nikolaev A.Y., et al. Parc: a cytoplasmic anchor for p53.

PMID: 10521492 by Moynihan T.P., et al. The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1.