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Transcription factor Sp8 Antibodies

AND SP8 ELISA kits, Transcription factor Sp8 Proteins

Many biological assays use antibodies to detect Transcription factor Sp8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor Sp8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor Sp8 antibodies...

We validate the specificity of these antibodies to Transcription factor Sp8 by testing them on tissues known to express SP8 positively and negatively. Browse below to find the SP8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SP8 Infographic by Boster Bio

SP8 protein infographic

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SP8 (NM_182700) Human Over-expression Lysate

Human

$960
Cat # LS221833
100 µg

SP8 Overview

Facts about Transcription factor Sp8.

SP8 3D structure

SP8 3D structure. Source: alphafold

Transcription factor Sp8 (SP8)

Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).

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Gene Information

Human
Gene Name:	SP8
Uniprot:	Q8IXZ3
Entrez:	221833

Gene Information

Family

Belongs to:

Sp1 C2H2-type zinc-finger protein family

Family

Alternative Names

transcription factor Sp8; BTD; Sp8 transcription factor

Molecular Weight

Mass (kDA):
48.674 kDA

Molecular Weight

Genomic Context


Human

Location:	7p21.1
Sequence:	7; NC_000007.14 (20782279..20786886, complement)

Subcellular Localizations

Nucleus.

Subcellular Localization

Diseases

Nervousness
Malignant Neoplasms
Limb Deformities, Congenital
Immunologic Deficiency Syndromes
Hemorrhage
Neoplasms
Hiv Infections
Acquired Immunodeficiency Syndrome
Neoplasm Metastasis
Melanoma
Ectrodactyly
Pain
Brain Injuries

Cleft Palate
Liver Neoplasms
Uveal Melanoma
Primary Dysmenorrhea
Cerebrovascular Accident
Dental Plaque
Cleft Lip

Disease

Pathways

Limb Development
Cell Adhesion
Neurogenesis
Localization
Regionalization
Pathogenesis
Olfactory Bulb Interneuron Development
Cell Proliferation
Head Development
Cell Development
Brain Development
Immune Response
Ossification

Dna Replication
Menstruation
Limb Morphogenesis
Cell Death
Neuropore Closure
Cell Growth
Cognition

Pathways

PTMs

Cleavage

Methylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SP8

References

PMID: 15533246 by Milona M.-A., et al. Genomic structure and cloning of two transcript isoforms of human Sp8.