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- Table of Contents
Facts about Juxtaposed with another zinc finger protein 1.
Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity).
Human | |
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Gene Name: | JAZF1 |
Uniprot: | Q86VZ6 |
Entrez: | 221895 |
Belongs to: |
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No superfamily |
JAZF zinc finger 1; juxtaposed with another zinc finger gene 1; juxtaposed with another zinc finger protein 1; TAK1-interacting protein 27; TIP27ZNF802DKFZp761K2222; Zinc finger protein 802
Mass (kDA):
27.079 kDA
Human | |
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Location: | 7p15.2-p15.1 |
Sequence: | 7; NC_000007.14 (27830573..28180795, complement) |
Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine.
Nucleus.
PMID: 15302918 by Nakajima T., et al. TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4.
PMID: 11371647 by Koontz J.I., et al. Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors.