Sorting nexin-18 Antibodies

AND SNX18 ELISA kits, Sorting nexin-18 Proteins

Many biological assays use antibodies to detect Sorting nexin-18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorting nexin-18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorting nexin-18 antibodies...

We validate the specificity of these antibodies to Sorting nexin-18 by testing them on tissues known to express SNX18 positively and negatively. Browse below to find the SNX18 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNX18 Infographic by Boster Bio

All SNX18 Products

Product

Figures

Specificity

Applications

Price

Anti-Sorting nexin-18 SNX18 Antibody

Human, Mouse, Rat

$405
Cat # A09010
100ul

SNX18 (NM_001102575) Human Over-expression Lysate

Human

$960
Cat # LS112574
100 µg

Anti-SNX18 Antibody Picoband™

Human, Rat

ELISA, WB

$370
Cat # A09010-2
100 μg/vial

SNX18 Overview

Facts about Sorting nexin-18.

SNX18 3D structure. Source: alphafold

Sorting nexin-18 (SNX18)

Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis.

Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis.

Gene Information

Human
Gene Name:	SNX18
Uniprot:	Q96RF0
Entrez:	112574

Family

Belongs to:

sorting nexin family

Alternative Names

FLJ11997; FLJ61062; MGC150827; MGC150829; SH3 and PX domain-containing protein 3B; SH3PX2; SH3PXD3BFLJ32560; SNAG1; sorting nexin 18; sorting nexin associated golgi protein 1; sorting nexin-18; Sorting nexin-associated Golgi protein 1

Molecular Weight

Mass (kDA):
68.894 kDA

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (54517759..54619249)

Subcellular Localizations

Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.

Diseases

Nervousness
Glioma
Wiskott-aldrich Syndrome

Interacting Proteins

RAB11FIP5

Pathways

Endocytosis
Clathrin-mediated Endocytosis
Localization
Transport
Mitosis
Metaphase
Macropinocytosis

Abscission
Cytokinesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNX18

References

PMID: 18411244 by Haberg K., et al. SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1- positive endosomal trafficking.

PMID: 20491914 by Baumann C., et al. The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain.