SNRNP70 Antibodies

AND SNRNP70 ELISA kits, SNRNP70 Proteins

Many biological assays use antibodies to detect SNRNP70, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRNP70 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRNP70 antibodies...

We validate the specificity of these antibodies to SNRNP70 by testing them on tissues known to express SNRNP70 positively and negatively. Browse below to find the SNRNP70 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRNP70 Infographic by Boster Bio

All SNRNP70 Products

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Specificity

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Price

SNRNP70 Small Nuclear Ribonucleoprotein 70kDa Human Recombinant Protein

Human

$250
Cat # PROTP08621
5ug, 20ug, 1mg

Anti-SNRNP70 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03527
100ul

SNRP70 (SNRNP70) (NM_003089) Human Over-expression Lysate

Human

$628
Cat # LS006625
100 µg

Anti-SNRNP70 Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03527-2
100 µg/vial

SNRNP70 Overview

Facts about U1 small nuclear ribonucleoprotein 70 kDa.

SNRNP70 3D structure. Source: alphafold

U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70)

Part of the spliceosomal U1 snRNP, which is essential for comprehension of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome (PubMed:19325628, PubMed:25555158). SNRNP70 binds to the loop that I region of U1-snRNA (PubMed:2467746, PubMed:19325628, PubMed:25555158).

Gene Information

Human
Gene Name:	SNRNP70
Uniprot:	P08621
Entrez:	6625

Family

Belongs to:

No superfamily

Alternative Names

RNPU1ZU170K; RPU1U1AP; small nuclear ribonucleoprotein 70kDa (U1); Snp1; snRNP70; SNRP70U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70Ksmall nuclear ribonucleoprotein 70kDa (RNP antigen); U1AP1; U1RNP

Molecular Weight

Mass (kDA):
51.557 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49085451..49108606)

Subcellular Localizations

Nucleus speckle. Nucleus, nucleoplasm. Colocalizes with SCNM1 and LUC7L2 in nuclear speckles.

Diseases

Autoimmune Reaction
Lupus Erythematosus, Systemic
Autoimmunity
Autoimmune Diseases
Connective Tissue Diseases
Mixed Connective Tissue Disease
Neoplasms
Lupus Nephritis
Cytomegalovirus Infections
Malignant Neoplasms
Glomerulonephritis
Proteinuria Of Undiagnosed Cause
Kidney Diseases

Malignant Neoplasm Of Breast
Lung Diseases
Pancytopenia
Lung Diseases, Interstitial
Carcinoma
Lupus Erythematosus, Cutaneous
Nephritis

Interacting Proteins

CLK2
SMN1
SRPK2
SRSF1
SRSF2

TIA1

Pathways

Cell Death
Immune Response
Secretion
Proteolysis
Mrna Processing
Localization
Pathogenesis
Cell Recognition
Transport
Protein Phosphorylation
Response To Peptide
Regulation Of Gene Expression
Nuclear Export

Execution Phase Of Apoptosis
Mrna Splicing
Mrna Transcription
Phagocytosis
Cell Differentiation
Lymphocyte Proliferation
Cell Proliferation

PTMs

Phosphorylation

Cleavage

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRNP70

References

PMID: 3028775 by Theissen H., et al. Cloning of the human cDNA for the U1 RNA-associated 70K protein.

PMID: 2447561 by Spritz R.A., et al. The human U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding.