SNRPA Antibodies

AND SNRPA ELISA kits, SNRPA Proteins

Many biological assays use antibodies to detect SNRPA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRPA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRPA antibodies...

We validate the specificity of these antibodies to SNRPA by testing them on tissues known to express SNRPA positively and negatively. Browse below to find the SNRPA antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRPA Infographic by Boster Bio

All SNRPA Products

Product

Figures

Specificity

Applications

Price

Anti-SNRPA Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A08780
100ul

Anti-U1A SNRPA Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A08780-1
100ul

Anti-U1A Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M08780-1
100 μl/vial

U1A (SNRPA) (NM_004596) Human Over-expression Lysate

Human

$628
Cat # LS006626
100 µg

Anti-U1A/SNRPA Antibody Picoband™

+18

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A08780-2
100 μg/vial

SNRPA Overview

Facts about U1 small nuclear ribonucleoprotein A.

SNRPA 3D structure. Source: alphafold

U1 small nuclear ribonucleoprotein A (SNRPA)

Component of the spliceosomal U1 snRNP, which is vital for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA.

This interaction is necessary for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA.

Gene Information

Human
Gene Name:	SNRPA
Uniprot:	P09012
Entrez:	6626

Family

Belongs to:

RRM U1 A/B'' family

Alternative Names

Mud1; small nuclear ribonucleoprotein polypeptide A; U1 snRNP A; U1 snRNP-specific protein A; U1-AU1 small nuclear ribonucleoprotein A; U1AU1 small nuclear RNP-specific A

Molecular Weight

Mass (kDA):
31.28 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40751203..40765389)

Subcellular Localizations

Nucleus.

Diseases

Liver Carcinoma
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Polyendocrinopathies, Autoimmune
Malignant Hyperpyrexia Due To Anesthesia
Dystrophy
Carcinoma
Central Core Myopathy (disorder)
Myopathy
Prostatic Neoplasms

Malignant Neoplasms
Neoplasms
Liver Neoplasms
Mammary Neoplasms
Myotonic Dystrophy

Interacting Proteins

CIRBP
GABPB1
HNRNPK
LENG8
METTL13

MTUS2
NDUFAF3
PCBP1
PCBP2
PTBP1

QKI
RBM3
RBMX
RBPMS2
SFPQ

SNRPA1
TIA1
TRIM27
TRIR
U2AF2

Pathways

Cell Proliferation
Mrna Processing
Hypersensitivity
Localization

PTMs

Acetylation

Methylation

Phosphoprotein

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRPA

References

PMID: 1831431 by Nelissen R.L.H., et al. Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein.

PMID: 2962859 by Sillekens P.T.G., et al. cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.