SNRNP200 Antibodies

AND SNRNP200 ELISA kits, SNRNP200 Proteins

Many biological assays use antibodies to detect SNRNP200, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRNP200 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRNP200 antibodies...

We validate the specificity of these antibodies to SNRNP200 by testing them on tissues known to express SNRNP200 positively and negatively. Browse below to find the SNRNP200 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRNP200 Infographic by Boster Bio

All SNRNP200 Products

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Anti-SNRNP200 Antibody Picoband®

+19

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04514-2
100 μg/vial

SNRNP200 Overview

Facts about U5 small nuclear ribonucleoprotein 200 kDa helicase.

SNRNP200 3D structure. Source: alphafold

U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200)

RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly.

Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome.

Gene Information

Human
Gene Name:	SNRNP200
Uniprot:	O75643
Entrez:	23020

Family

Belongs to:

helicase family

Alternative Names

ASCC3L1; BRR2 homolog; BRR2; FLJ11521; HELIC2; KIAA0788; RP33; small nuclear ribonucleoprotein 200kDa (U5); U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5-200KD

Molecular Weight

Mass (kDA):
244.508 kDA

Genomic Context


Human

Location:	2q11.2
Sequence:	2; NC_000002.12 (96274338..96305546, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus.

Diseases

Retinitis Pigmentosa
Abnormal Degeneration
Disorder Of Eye
Retinal Degeneration
Degenerative Disorder
Visual Impairment

Blind Vision

Interacting Proteins

CHMP1B
PRPF8
RNF113A
SNRNP40
WBP4

Pathways

Pathogenesis
Rna Splicing
Mrna Splicing

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRNP200

References

PMID: 16723661 by Liu S., et al. The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.

PMID: 8670905 by Lauber J., et al. The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases.